Cedars-Sinai Medical Center

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A BI-WEEKLY PUBLICATION FROM THE CEDARS-SINAI CHIEF OF STAFF June 24, 2011 Issue | Archived Issues

Lyden Named Associate Editor of Stroke Journal

Physician News

Patrick D. Lyden, M.D.

Dr. Lyden, chair of the Department of Neurology at Cedars-Sinai Medical Center and an expert in stroke research and intervention, has been named Associate Editor of the International Journal of Stroke, one of the top peer-reviewed publications on the subject.

The journal focuses on research that has practical, clinical applications. It covers topics of global importance, provides region-specific features and includes stroke-related news from all parts of the world. Associate editors from Europe, Asia, North America and South America coordinate journal content.

Surasak Phuphanich, M.D.

Dr. Phuphanich recently presented at the American Society of Clinical Oncology (ASCO) annual meeting on June 4. He discussedglioma-associated antigens connected with prolonged survival in a phase I study of ICT-107 for patients with newly diagnosed glioblastoma, as a part of the Central Nervous System Tumors series.

ICT-107 targets six antigens found on glioblastoma cells, three of which also are found on cancer stem cells. Those cells widely are believed to be the original source of tumor cells, enabling them to resist treatment and recur. The study revealed that all 16 patients had at least three of the targeted antigens and 75 percent had all six. Patients who had four of the antigens (MAGE-A1, AIM2, gp100 and HER2) had better immune responses and longer progression-free survival rates.

Dr. Phuphanich is the director of the Neuro-Oncology Program in the Department of Neurosurgery and Department of Neurology at Cedars-Sinai Medical Center.

David Rimoin, M.D., Ph.D.

Dr. Rimoin recently received the Johns Hopkins University Alumni Associations’ Distinguished Alumnus Award.

Dr. Rimoin is chair of the Cedars-Sinai Medical Genetics Research Institute and holds the Steven Spielberg Family Chair in Pediatrics. He also serves as director of the International Skeletal Dysplasia Registry.