Cedars-Sinai Medical Center

medical staff pulse newsletter

Text size: A A A
A BI-WEEKLY PUBLICATION FROM THE CEDARS-SINAI CHIEF OF STAFF March 27, 2015 | Archived Issues

Recognition for Arena, Charlton, Jones, Karlan, Spiegel

Elizabeth A. Arena, MD, has been awarded board certification in complex general surgical oncology, Timothy P. Charlton, MD, represented the American Academy of Orthopaedic Surgeons this month in Washington, Heather Jones, MD, has received a grant from the National Institutes of Health for lung research, Beth Y. Karlan, MD, will receive the 2015 Distinguished Service Award from the Society of Gynecologic Oncology, and Brennan Spiegel, MD, MSHS, has been named co-editor-in-chief of The American Journal of Gastroenterology.

» Read more


Meetings and Events


Grand Rounds

Click here to view upcoming grand rounds.


Upcoming CME Conferences

Click below to view a complete list of all scheduled Continuing Medical Education conferences.

CME Newsletter - March 2015 (PDF)


Milestones

Do you know of a significant event in the life of a medical staff member? Please let us know, and we'll post these milestones in Medical Staff Pulse. Also, feel free to submit comments on milestones, and we'll post the comments in the next issue. Click here to email us your milestones and comments.

» Read more

Share Your News

Won any awards or had an article accepted for publication? Share your news about professional achievements and other items of interest.

Click here to share your news

Gut Bacteria May Limit Effect of Bariatric Surgery

The benefits of weight-loss surgery, along with a treatment plan that includes exercise and dietary changes, are well documented. In addition to a significant decrease in body mass, many patients find their risk factors for heart disease are drastically lowered and blood sugar regulation is improved for those with Type 2 diabetes.

Ruchi Mathur, MD

Some patients, however, do not experience the optimal weight loss from bariatric surgery. The presence of a specific methane gas-producing organism in the gastrointestinal tract may account for a decrease in optimal weight loss, according to new research by Ruchi Mathur, MD, director of the Cedars-Sinai Anna and Max Webb and Family Diabetes Outpatient Treatment and Education Center.

"We looked at 156 obese adults who either had Roux-en-Y bypass surgery or received a gastric sleeve. Four months after surgery, we gave them a breath test, which provides a way of measuring gases produced by microbes in the gut," Mathur said. "We found that those whose breath test revealed higher concentrations of both methane and hydrogen were the ones who had the lowest percentage of weight loss and lowest reduction in BMI (body mass index) when compared to others in the study."

The methane-producing microorganism methanobrevibacter smithii is the biggest maker of methane in the gut, Mathur said, and it may be the culprit thwarting significant weight loss in bariatric patients. Mathur and her colleagues are conducting further studies to explore the role this organism plays in human metabolism.

While that research continues, bariatric patients may still have options to improve weight loss after surgery.

"Identifying individuals with this pattern of intestinal gas production may allow for interventions through diet. In the future, there may be therapeutic drugs that can improve a patient's post-surgical course and help them achieve optimal weight loss," Mathur said.

The study, "Intestinal Methane Production is Associated with Decreased Weight Loss Following Bariatric Surgery," was done in collaboration with the Mayo Clinic. Mathur presented the paper this month at the 97th annual meeting of the Endocrine Society in San Diego.