Cedars-Sinai Medical Center

medical staff pulse newsletter

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A BI-WEEKLY PUBLICATION FROM THE CEDARS-SINAI CHIEF OF STAFF September 7, 2018 | Archived Issues

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Milestones

Do you know of a significant event in the life of a medical staff member? Please let us know, and we'll post these milestones in Medical Staff Pulse. Also, feel free to submit comments on milestones, and we'll post the comments in the next issue.

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FDA Issues Warnings and Labeling Change

The U.S. Food and Drug Administration(FDA)  is warning that the antibiotic Zithromax, Zmax (azithromycin) should not be given long-term to prevent a certain inflammatory lung condition in patients with cancers of the blood or lymph nodes who undergo a donor stem cell transplant. Results of a clinical trial found an increased rate of relapse in cancers affecting the blood and lymph nodes, including death, in these patients.

The FDA website has more information.

FDA: Safety Label Changes for Fluoroquinolones

The FDA is requiring safety labeling changes for a class of antibiotics called fluoroquinolones to strengthen the warnings about the risks of mental health side effects and serious blood sugar disturbances—and make these warnings more consistent across the labeling for all fluoroquinolones taken by mouth or given by injection.

The FDA website has more information.

FDA: Serious Rare Infection Possible With SGLT2 Inhibitors

The FDA is warning that cases of a rare, but serious, infection of the genitals and surrounding area have been reported with the class of Type 2 diabetes medicine called sodium-glucose cotransporter-2 (SGLT2) inhibitors. This serious rare infection, called necrotizing fasciitis of the perineum, is also referred to as Fournier’s gangrene.

The FDA website has more information.