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PRODUCED BY AND FOR MEMBERS OF THE DEPARTMENT OF SURGERY November 2012 | Archived Issues

Featured publication

A recent publication by Dolores Di Vizio, MD, PhD, "Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease," was featured on the cover of the American Journal of Pathology.

Di Vizio et al., Am. J. Pathol Vol. 181, No. 5, November 2012, in press

Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease.

Photomicrograph of human prostate cancer cells with their plasma membranes fluorescently labeled showing bulbous membrane protrusions and large microvesicles, or oncosomes, derived from them and released into the surroundings. These are features of the amoeboid tumor cell phenotype, which appears to reflect aggressive disease in vivo.

American Journal of Pathology November Cover (PDF)