Cedars-Sinai

Medical Staff Pulse Newsletter

New Guidelines for Vancomycin Dosing Start Feb. 18

Based on updated guidelines, the Department of Pharmacy Services is modernizing the process by which it doses vancomycin [area under the curve-based dosing (AUC24)], beginning Feb. 18. Benefits with AUC24 dosing include: improved efficacy and safety, reduced need for vancomycin level monitoring and reduced total daily doses of vancomycin.

  • Ordering vancomycin in CS-Link™ will remain the same for providers. Continue to order the “VANCOMYCIN PER PHARMACY” ERx [4080310001] in CS-Link.
  • Pharmacists will use vancomycin serum levels to calculate an AUC24 (a marker of total drug exposure over 24 hours).
  • To streamline lab orders, CS-Link lab orders for LAB41 (vancomycin peak) and LAB39 (vancomycin trough) will be removed—only LAB40 (vancomycin level) will remain in CS-Link.

If you have any questions, contact the antimicrobial stewardship pharmacists at 310-423-5352 or GroupPharmacyAUR@cshs.org.