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FDA Warns About SGLT2 Inhibitors, Contrast Media

Pharmacy Focus

A review by the U.S. Food and Drug Administration has resulted in additional warnings on the labels of sodium-glucose cotransporter-2 (SGLT2) inhibitors about the risks of too much acid in the blood and of serious urinary tract infections. Also, the FDA is advising that rare cases of underactive thyroid have been reported in infants following the use of contrast media containing iodine for X-rays and other medical imaging procedures. 

Mark Your Calendar

Surgery Grand Rounds

Click the "read more" to see information about upcoming Surgery Grand Rounds.

Grand Rounds

Click here to view a schedule of all upcoming grand rounds.

Education Schedule

Click the PDF links below to see the Department of Surgery's education schedule.

Education Schedule - December 2015 (PDF)  

Surgery Scheduling

Click the "read more" for hours and contact information for surgery scheduling.

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Antimicrobial Stewardship Alerts in CS-Link

From Chris Ng, MD, Chief of Staff

In an effort to reduce antimicrobial resistance and improve patient safety, Cedars-Sinai is launching best practice alerts in CS-Link™ for patients receiving selected antibiotics for three or more days. Increasing rates of drug-resistant infections and a limited supply of new antibiotics have placed new emphasis on promoting the safe, efficient use of antibiotics at healthcare organizations across the nation. Although antibiotics can save lives, they can also lead to complications including drug reactions and other serious infections such as Clostridium difficile.

This "three-day alert" will be implemented in phases, beginning in four test-of-change units — 4 Northwest, 5 Northeast, 5 Southwest and 8 Southwest — on Nov. 17. It will launch housewide for vancomycin on Dec. 8. The alerts are meant to help clinicians appropriately modify empiric antibiotic regimens after additional clinical information becomes available.

As part of the alerts, clinicians who prescribe antibiotics will be prompted to indicate their plans to discontinue, modify or continue use on the third day of a patient's treatment.

If treatment is continued, clinicians will need to document their reasons for continued therapy. The alert will also include a reference link to the Cedars-Sinai empiric antibiotic treatment guidelines to assist with antibiotic selection. In some cases, clinicians may also be contacted by a pharmacist to discuss antimicrobial therapy.

Should you have any questions or concerns about this project, please contact the antimicrobial stewardship pharmacist at 310-433-8700, ext. 3-5352 or by pager 1462.

We appreciate your continued collaboration in keeping our patients safe by ensuring they receive no more and no less antibiotic treatment than necessary. We will be soliciting your feedback as we move forward with this initiative to help guide future antimicrobial stewardship interventions. We also encourage you to take advantage of the Centers for Disease Control and Prevention's resources on antimicrobial stewardship as it celebrates Get Smart About Antibiotics Week next week.

Thank you for your support of this critical patient safety initiative.